Some things you might want to think about ahead of time and watch out for: lax building codes (meaning open stairwells and other dangers), beach and pool safety, food and water safety, and transportation.
More specifically, you will often find that the taxis do not have rear seatbelts, they certainly won’t have a LATCH system, and sometimes, even with seatbelts, they won’t allow you to install your car seat.
Hire a car for day trips, or any days that you are planning to jump around to several sites within one day, and use the car seat instead of hopping from taxi to taxi.
Anywhere you stay in Thailand will have a water kettle for boiling water (usually electric), but boiling the tap water will not make it 100% safe to drink.