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Highlights
American College of Physicians Issues New Breast Cancer Screening Guidelines

The American College of Physicians has issued new screening guidelines for women of average risk of developing breast cancer. The guidelines suggest that, for the average-risk woman under 50 years old who does not have breast symptoms, the potential for harm in breast cancer screenings outweigh the benefits

Metastatic Non-Clear Cell Renal Cancer Patients Have Positive Response to Immunotherapy

Over the past decade, major progress has been made in treating metastatic clear cell renal cell carcinoma (ccRCC), with immunotherapy now a standard of care in ccRCC. However, progress has lagged behind for metastatic non-clear cell renal cell carcinoma (nccRCC), which affects only a fraction of all RCC patients, and is not well understood

Good QOL Outcomes Achieved After Extended Bifrontal Resection for Giant Meningiomas

Patients who underwent an extended bifrontal approach for resection of a giant anterior cranial base meningioma had improved processing speed postoperatively and no significant changes in nine other neuropsychological quality-of-life (QOL) indicators in a Cleveland Clinic study presented at the 2019 annual meeting of the North American Skull Base Society. “Given the impairment we expect to see with frontal tumors, our findings suggest that the extended bifrontal approach may be an improvement over traditional surgery,” says Cleveland Clinic neurosurgeon Pablo Recinos, MD, senior author of the study

The Microbiome of the Inflamed Aorta: What Can We Discern?

Noninfectious aortitis is usually result of primary systemic large-vessel vasculitis (LVV) such as giant cell arteritis (GCA) or Takayasu’s arteritis (TAK). But inflammation of the aorta may also present as “clinically isolated aortitis” (CIA), a noninfectious vasculitis restricted to the proximal thoracic aorta

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